SBI Workflow Overview

Simulation-Based Inference: A Practical Guide

We provide a practical guide for applying SBI methods, outlining a structured workflow with guidelines and diagnostic tools for every stage—from setting up simulators to validating results.

August 2025 · Michael Deistler*, Jan Boelts*, Peter Steinbach, Guy Moss, Thomas Moreau, Manuel Gloeckler, Pedro L. C. Rodrigues, Julia Linhart, Janne K. Lappalainen, Benjamin Kurt Miller, Pedro J. Gonçalves, Jan-Matthis Lueckmann, Cornelius Schröder, Jakob H. Macke
SBI Tutorial

Beyond Likelihoods: Bayesian Parameter Inference for Black-Box Simulators with sbi

A comprehensive hands-on tutorial at EuroSciPy 2025 teaching scientists and engineers how to use simulation-based inference (SBI) for Bayesian parameter estimation in complex simulators, providing full uncertainty quantification beyond simple best-fit approaches.

August 2025 · Jan Teusen

sbi reloaded: A toolkit for simulation-based inference workflows

We present sbi reloaded, a comprehensive update to the sbi Python package that provides researchers with state-of-the-art algorithms and tools for simulation-based inference workflows across scientific domains.

April 2025 · Jan Boelts*, Michael Deistler*, Manuel Gloeckler, Álvaro Tejero-Cantero, Jan-Matthis Lueckmann, Guy Moss, Peter Steinbach, Thomas Moreau, Fabio Muratore, Julia Linhart, Conor Durkan, Julius Vetter, Benjamin Kurt Miller, Maternus Herold, Abolfazl Ziaeemehr, Matthijs Pals, Theo Gruner, Sebastian Bischoff, Nastya Krouglova, Richard Gao, Janne K. Lappalainen, Bálint Mucsányi, Felix Pei, Auguste Schulz, Zinovia Stefanidi, Pedro Rodrigues, Cornelius Schröder, Faried Abu Zaid, Jonas Beck, Jaivardhan Kapoor, David S. Greenberg, Pedro J. Gonçalves, Jakob H. Macke

Mind the Gap: Methods and Applicability of Simulation-Based Inference

Internal seminar at TransferLab discussing recent advances in simulation-based inference methods and their practical applications across scientific domains.

March 2024 · Jan Teusen
SBI Training

Simulation-Based Inference Training

Hands-on training in Simulation-Based Inference (SBI), designed for applications in neuroscience, astrophysics, and biology. Developed in collaboration with the University of Tübingen and the TransferLab at the appliedAI Institute for Europe.

April 2023 · Jan Teusen and Maternus Herold
Mixed Neural Likelihood Estimation

Flexible and efficient simulation-based inference for models of decision-making

We propose a new method to perform simulation-based inference for mixed data e.g., with continuous and discrete data types, like they often occur in models of decision-making.

July 2022 · Jan Boelts, Jan-Matthis Lueckmann, Richard Gao, Jakob H. Macke

GATSBI: Generative Adversarial Training for Simulation-Based Inference

We introduce GATSBI, a method that combines generative adversarial networks with simulation-based inference to achieve better sample efficiency and accuracy in posterior estimation.

April 2022 · Poornima Ramesh, Jan-Matthis Lueckmann, Jan Boelts, Álvaro Tejero-Cantero, David S. Greenberg, Jakob H. Macke

Benchmarking Simulation-Based Inference

We present a benchmark suite for simulation-based inference, systematically evaluating different methods across tasks with varying dimensionality, simulation budgets, and amortization requirements.

April 2021 · Jan-Matthis Lueckmann, Jan Boelts, David S. Greenberg, Pedro J. Gonçalves, Jakob H. Macke

sbi: A toolkit for simulation-based inference

We introduce sbi, a Python package providing a unified interface for simulation-based inference methods, making these powerful techniques accessible to researchers across disciplines.

August 2020 · Álvaro Tejero-Cantero*, Jan Boelts*, Michael Deistler*, Jan-Matthis Lueckmann*, Conor Durkan*, Pedro J. Gonçalves, David S. Greenberg, Jakob H. Macke
sbi python package

sbi: Simulation-Based Inference

sbi is a Python package for simulation-based inference, providing a user-friendly interface to perform Bayesian parameter inference for simulator-based models with intractable likelihoods.

August 2020 · The sbi-dev team